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Overview
2,4-Dihydroxypyrimidine-5-carboxylic acid (Isoorotic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. 2,4-Dihydroxypyrimidine-5-carboxylic acid has been used to synthesize N1-alkylated uracil derivatives.
Chemical Properties
| Molecular Formula | C5H4N2O4 |
| Molecular Weight | 156.1 |
| CAS Numbers | 23945-44-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC(=O)C1=CNC(=O)NC1=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Shaffer PM, et al. Metabolism of pyrimidine deoxyribonucleosides in Neurospora crassa. J Bacteriol. 1975 Feb;121[2] 648-55.