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Overview
1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 ?M for native T-currents[1]. Additionally, 1-Octanol is recognized for its potential as a biofuel, possessing diesel-like properties[2].
Chemical Properties
| Molecular Formula | C8H18O |
| Molecular Weight | 130.23 |
| CAS Numbers | 111-87-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCCCCCCCO |
Storage and Handling
0C Short Term, -20C Long Term
References
Joksovic PM, et al. Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol implication of the protein kinase C pathway. Mol Pharmacol. 2010 Jan;77[1] 87-94.