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Overview
Diphenyl disulfide (Phenyl disulfide) shows anticancer activity in breast cancer cell lines.Diphenyl disulfide induces and enhances apoptosis in breast cancer cells through Bax protein hydrolysis activation and concomitant autophagy.Diphenyl disulfide inhibits cell proliferation and viability and reduces colony formation in a dose-dependent manner. Diphenyl disulfide can be used to treat breast cancer.
Chemical Properties
| Molecular Formula | C12H10S2 |
| Molecular Weight | 218.34 |
| CAS Numbers | 882-33-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | S(SC1=CC=CC=C1)C1=CC=CC=C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Nakamura YK, et al. Suppressing effects of S-methyl methanethiosulfonate and diphenyl disulfide on mitomycin C-induced somatic mutation and recombination in Drosophila melanogaster and micronuclei in mice. Mutat Res. 1997;385[1] 41-46.