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Overview
trans-Cyclohexane-1,2-diol (trans-1,2-Cyclohexanediol) has a synergistic retardation effect on percutaneous absorption and penetration of metronidazole (MTZ).
Chemical Properties
| Molecular Formula | C6H12O2 |
| Molecular Weight | 116.16 |
| CAS Numbers | 1460-57-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O[C@@H]1CCCC[C@H]1O |
Storage and Handling
0C Short Term, -20C Long Term
References
Zhang Y, et al. Effect of hydroxyl groups and rigid structure in 1,4-cyclohexanediol on percutaneous absorption of metronidazole. AAPS PharmSciTech. 2014 Aug;15[4] 973-80.