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Photochlor
AOB149402517
CAS: 149402-51-7
Chemical Name: (3S,4S)-14-Ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $50.15 | Total: $250.75 |
| 1 | 10 | $42.48 | Total: $424.80 |
| 1 | 25 | $35.99 | Total: $899.75 |
| 1 | 50 | $30.68 | Total: $1,534.00 |
| 1 | 100 | $26.55 | Total: $2,655.00 |
Overview
A lipophilic, second-generation, chlorin-based photosensitizer
Chemical Properties
| Molecular Formula | C39H48N4O4 |
| Molecular Weight | 636.82 |
| CAS Numbers | 149402-51-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (3S,4S)-14-Ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid |
| InChl Key | RBLODCJRUDEMCI-AMPGYZHFSA-N |
| InChl Code | InChI=1S/C39H50N4O4/c1-8-10-11-12-15-47-24(7)36-22(5)30-17-29-21(4)26(13-14-35(45)46)38(42-29)27-16-34(44)37-23(6)31(43-39(27)37)18-32-25(9-2)20(3)28(40-32)19-33(36)41-30/h17-19,21,24,26,31,40-41,43H,8-16H2,1-7H3,(H,45,46)/b28-19-,29-17-,32-18-/t21-,24?,26-,31?/m0/s1 |
| SMILES Code | O=C(O)CC[C@@H]([C@@H]/1C)C2=NC1=C/C3=C(C)C(C(OCCCCCC)C)=C(N3)/C=C4C(C)=C(CC)/C(N/4)=C/C5C(C)=C6C(N5)=C2CC6=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
HPPH; Photochlor; 2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a; 2-(1'-hexyloxyethyl)-2-devinylpyropheophorbide-a.
References
1) Sun G, Anderson MA, Gorospe EC, Leggett CL, Lutzke LS, Wong Kee Song LM, Levy M, Wang KK. Synergistic effects of photodynamic therapy with HPPH and gemcitabine in pancreatic cancer cell lines. Lasers Surg Med. 2012 Nov;44(9):755-61. doi: 10.1002/lsm.22073. Epub 2012 Sep 27. PubMed PMID: 23018618.
2) Nava HR, Allamaneni SS, Dougherty TJ, Cooper MT, Tan W, Wilding G, Henderson BW. Photodynamic therapy (PDT) using HPPH for the treatment of precancerous lesions associated with Barrett's esophagus. Lasers Surg Med. 2011 Sep;43(7):705-12. doi: 10.1002/lsm.21112. PubMed PMID: 22057498; PubMed Central PMCID: PMC3218433.