Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Primary Cells
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $121.55 | Total: $607.75 |
| 1 | 10 | $102.96 | Total: $1,029.60 |
| 1 | 25 | $87.23 | Total: $2,180.75 |
| 1 | 50 | $74.36 | Total: $3,718.00 |
| 1 | 100 | $64.35 | Total: $6,435.00 |
Overview
MSC-4381 (MCT4-IN-1) is an orally available and selectively modeled highly potent inhibitor of monocarboxylic acid transporter protein 4 (MCT4SLC16A3) with potential anticancer and antitumor activity for the study of osteosarcoma.
Chemical Properties
| Molecular Formula | C26H20ClN3O6S |
| Molecular Weight | 537.97 |
| CAS Numbers | 2445185-57-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCOc1ccc(c2ncccc12)S(=O)(=O)Nc1ccc(Cl)cc1C#Cc1cnc(cc1OC)C(O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Timo Heinrich, et al. Discovery of 5-{2-[5-Chloro-2-[5-ethoxyquinoline-8-sulfonamido]phenyl]ethynyl}-4-methoxypyridine-2-carboxylic Acid, a Highly Selective in Vivo Useable Chemical Probe to Dissect MCT4 Biology. J Med Chem. 2021 Aug 26;64[16] 11904-11933.