Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
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- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $69.70 | Total: $348.50 |
| 1 | 10 | $59.04 | Total: $590.40 |
| 1 | 25 | $50.02 | Total: $1,250.50 |
| 1 | 50 | $42.64 | Total: $2,132.00 |
| 1 | 100 | $36.90 | Total: $3,690.00 |
Overview
PQR620 is a novel potent and selective, brain penetrant inhibitor of mTORC12.
Chemical Properties
| Molecular Formula | C21H25F2N7O2 |
| Molecular Weight | 445.47 |
| CAS Numbers | 1927857-56-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [H][C@]12CC[C@]([H])(COC1)N2c1nc(nc(n1)-c1cnc(N)cc1C(F)F)N1[C@@]2([H])CC[C@]1([H])COC2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Florent Beaufils, et al. Abstract 1336 Structure-activity relationship studies, synthesis, and biological evaluation of PQR620, a highly potent and selective mTORC12 inhibitor. Cancer Research; 2016 Apr 16-20.