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![[Sar9,Met(O2)11]-Substance P acetate](https://img.aobious.com/img/p/4/7/5/1/2/47512-large_default.webp "[Sar9,Met(O2)11]-Substance P acetate")
![[Sar9,Met(O2)11]-Substance P acetate](https://img.aobious.com/img/p/4/7/5/1/2/47512.jpg "[Sar9,Met(O2)11]-Substance P acetate")
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $66.30 | Total: $331.50 |
| 1 | 10 | $56.16 | Total: $561.60 |
| 1 | 25 | $47.58 | Total: $1,189.50 |
| 1 | 50 | $40.56 | Total: $2,028.00 |
| 1 | 100 | $35.10 | Total: $3,510.00 |
Overview
[Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P acetate and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P acetate is the sole to produce grooming.
Chemical Properties
| Molecular Formula | C67H106N18O17S |
| Molecular Weight | 1467.75 |
| CAS Numbers | 3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C([C@H](CCCCN)NC([C@H]1N(C([C@@H](N)CCCNC(N)=N)=O)CCC1)=O)N(CCC2)[C@@H]2C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@H](C(N(C)CC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCS(C)(=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)=O.CC(O)=C.[O] |
Storage and Handling
0C Short Term, -20C Long Term
References
Cellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127[3] 717-28.