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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $139.40 | Total: $697.00 |
| 1 | 10 | $118.08 | Total: $1,180.80 |
| 1 | 25 | $100.04 | Total: $2,501.00 |
| 1 | 50 | $85.28 | Total: $4,264.00 |
| 1 | 100 | $73.80 | Total: $7,380.00 |
Overview
Spexin acetate is a potent galanin receptor 23 (GAL2GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Attenuates LH secretion in goldfish. Exhibits anxiolytic effects in vivo.
Chemical Properties
| Molecular Formula | C76H117N19O22S |
| Molecular Weight | 1680.94 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(O)=O.O=C(O)CC[C@@H](C(N)=O)NC([C@H](C)NC(CNC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CC(C)C)NC([C@H](CCSC)NC([C@H](C)NC([C@H](CCC(N)=O)NC([C@H]2N(C([C@H]([C@H](O)C)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CC(N)=O)N)=O)=O)=O)CCC2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Walewski et al [2014] Spexin is a novel human peptide that reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents with diet-induced obesity Obesity [Silver Spring] 22 1643 PMID