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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $106.25 | Total: $531.25 |
| 1 | 10 | $90.00 | Total: $900.00 |
| 1 | 25 | $76.25 | Total: $1,906.25 |
| 1 | 50 | $65.00 | Total: $3,250.00 |
| 1 | 100 | $56.25 | Total: $5,625.00 |
Overview
EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively. EHT 1610 has an inhibitory effect on leukemia, regulating cell cycle and inducing cell apoptosis.
Chemical Properties
| Molecular Formula | C18H14FN5O2S |
| Molecular Weight | 383.4 |
| CAS Numbers | 1425945-60-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COC(=N)c1nc2ccc3ncnc(Nc4ccc(OC)cc4F)c3c2s1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Chaikuad A, et al. An Unusual Binding Model of the Methyl 9-Anilinothiazolo[5,4-f] quinazoline-2-carbimidates [EHT 1610 and EHT 5372] Confers High Selectivity for Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases. J Med Chem. 2016;59[22] 10315-1032