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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $58.65 | Total: $293.25 |
| 1 | 10 | $49.68 | Total: $496.80 |
| 1 | 25 | $42.09 | Total: $1,052.25 |
| 1 | 50 | $35.88 | Total: $1,794.00 |
| 1 | 100 | $31.05 | Total: $3,105.00 |
Overview
Nimbolide suppresses CDK4CDK6 kinase activity. Nimbolide inhibits the NF-?B, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-?B. Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica L).
Chemical Properties
| Molecular Formula | C27H30O7 |
| Molecular Weight | 466.52 |
| CAS Numbers | 25990-37-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C[C@]12[C@]3([C@]([C@@]4([C@](C)([C@@H]1CC(OC)=O)C=5[C@](O4)(C[C@H](C5C)C=6C=COC6)[H])[H])(OC(=O)[C@]3(C)C=CC2=O)[H])[H] |
Storage and Handling
0C Short Term, -20C Long Term
References
Bodduluru LN, et al. Chemopreventive and therapeutic effects of nimbolide in cancer the underlying mechanisms. Toxicol In Vitro. 2014 Aug;28[5] 1026-35.