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DP2392-E10
AOB11602
CAS: 340296-14-2
Chemical Name: Ethyl 5-(4-nitrophenyl)-4,6-dioxo-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate
100 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $109.65 | Total: $548.25 |
| 1 | 10 | $92.88 | Total: $928.80 |
| 1 | 25 | $78.69 | Total: $1,967.25 |
| 1 | 50 | $67.08 | Total: $3,354.00 |
| 1 | 100 | $58.05 | Total: $5,805.00 |
Overview
Novel anti-influenza agent, inhibiting replication of a broad range of influenza A subtypes by inhibiting the nuclear export function of the viral nucleoprotein-nuclear export signal 3 (NP-NES3) domain
Chemical Properties
| Molecular Formula | C14H10N4O6 |
| Molecular Weight | 330.26 |
| CAS Numbers | 340296-14-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | Ethyl 5-(4-nitrophenyl)-4,6-dioxo-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate |
| InChl Key | KJAJWCHANQMLIT-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C14H10N4O6/c1-2-24-14(21)11-9-10(15-16-11)13(20)17(12(9)19)7-3-5-8(6-4-7)18(22)23/h3-6H,2H2,1H3,(H,15,16) |
| SMILES Code | CCOC(=O)C1=C2C(=NN1)C(=O)N(C2=O)C3=CC=C(C=C3)[N+](=O)[O-] |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
DP2392-E10; DP2392E10; DP2392 E10
References
1) Alaa Shaikhqasem et al., Characterization of Inhibition Reveals Distinctive Properties for Human and Saccharomyces cerevisiae CRM1, J. Med. Chem. 2020, 63, 14, 7545–7558
2) Nopporn Chutiwitoonchai et al., Inhibition of CRM1-mediated nuclear export of influenza A nucleoprotein and nuclear export protein as a novel target for antiviral drug development, Virology. 2017 Jul; 507: 32–39.