Synucleozid hydrochloride

Synucleozid hydrochloride

AT13049L

CAS 2741856-68-6

More details

1000 Items

$218.40

$218.40 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $142.80 Total: $714.00
110 $120.96 Total: $1,209.60
125 $102.48 Total: $2,562.00
150 $87.36 Total: $4,368.00
1100 $75.60 Total: $7,560.00

Overview

Synucleozid hydrochloride inhibits the translation of the intrinsically disordered protein ?-synuclein by targeting its structured mRNA. Synucleozid hydrochloride targets the IRE structure and inhibits SNCA translation in cells, and can be used to study Alzheimer's disease.

Chemical Properties

Molecular FormulaC22H21ClN6
Molecular Weight404.9
CAS Numbers2741856-68-6
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.N=C(N)C1=CC=C(C=C1)NC=2C=CC(=CC2)C3=CC4=CC=C(C=C4N3)C(=N)N

Storage and Handling

0C Short Term, -20C Long Term

References

Zhang P, et al. Translation of the intrinsically disordered protein ?-synuclein is inhibited by a small molecule targeting its structured mRNA.Proc Natl Acad Sci U S A. 2020 Jan 21;117[3] 1457-1467.