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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $92.65 | Total: $463.25 |
| 1 | 10 | $78.48 | Total: $784.80 |
| 1 | 25 | $66.49 | Total: $1,662.25 |
| 1 | 50 | $56.68 | Total: $2,834.00 |
| 1 | 100 | $49.05 | Total: $4,905.00 |
Overview
BAY-8400 is a potent, selective, and orally active DNA-dependent protein kinase (DNA-PK) inhibitor (IC50 = 81 nM) that demonstrates synergistic efficacy when combined with targeted alpha therapies. BAY-8400 is applicable for cancer research [1].
Chemical Properties
| Molecular Formula | C21H17F2N5O |
| Molecular Weight | 393.39 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | FC(F)C1=CN=CC(C2=CC=C(N=CC3=NN=C(C4=CCCOCC4)N35)C5=C2)=C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Berger M, et al. BAY-8400 A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies [published online ahead of print, 2021 Aug 24]. J Med Chem. 2021;10.1021acs.jmedchem.1c00762.