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NSC15765 (DNA2-IN-C5)
AOB9082
CAS No: 35973-25-2
Chemical Name: NSC15765; 4-Hydroxy-8-nitroquinoline-3-carboxylic acid; 8-Nitro-4-oxo-1H-quinoline-3-carboxylic acid
AOBIOUS launched this product in 2017
CITATIONS - Publications That Use AOBIOUS Product
720 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Overview
Novel specific inhibitor of DNA2 nuclease activity
Chemical Properties
| Molecular Formula | C10H6N2O5 |
| Molecular Weight | 234.17 |
| CAS Numbers | 35973-25-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 8-Nitro-4-oxo-1H-quinoline-3-carboxylic acid |
| InChl Key | BMIZBCVEHSUUNO-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C10H6N2O5/c13-9-5-2-1-3-7(12(16)17)8(5)11-4-6(9)10(14)15/h1-4H,(H,11,13)(H,14,15) |
| SMILES Code | O=C(C1=CNC2=C(C=CC=C2[N+]([O-])=O)C1=O)O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
DNA2-IN-C5; DNA2 IN C5; DNA2INC5; NSC15765; NSC-15765; NSC 15765
References
Liu W, Zhou M, Li Z, Li H, Polaczek P, Dai H, Wu Q, Liu C, Karanja KK, Popuri V, Shan SO, Schlacher K, Zheng L, Campbell JL, Shen B. A Selective Small Molecule DNA2 Inhibitor for Sensitization of Human Cancer Cells to Chemotherapy. EBioMedicine. 2016 Apr;6:73-86. doi: 10.1016/j.ebiom.2016.02.043. Epub 2016 Mar 10. PubMed PMID: 27211550; PubMed Central PMCID: PMC4856754
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