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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $190.40 | Total: $952.00 |
| 1 | 10 | $161.28 | Total: $1,612.80 |
| 1 | 25 | $136.64 | Total: $3,416.00 |
| 1 | 50 | $116.48 | Total: $5,824.00 |
| 1 | 100 | $100.80 | Total: $10,080.00 |
Overview
Emprumapimod (PF-07265803) is an orally active and specific inhibitor of mitogen-activated protein kinase p38? MAPK, inhibits LPS-induced production of IL-6, and can be used to study dilated cardiomyopathy induced by the LMNA gene.
Chemical Properties
| Molecular Formula | C24H29F2N5O3 |
| Molecular Weight | 473.52 |
| CAS Numbers | 765914-60-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(C(C)C)N1C=2C(=CC(OC3=C(F)C=C(F)C=C3)=C(C(N[C@@H](CCN(C)C)C(N)=O)=O)C2)C=N1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Dale Wright, et al. ARRY-797, a Potent and Selective Inhibitor of p38 Map Kinase, Inhibits LPS-Induced IL-6 and In Vivo Growth of RPMI-8226 Human Multiple Myeloma Cells.