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Overview
(-)-Bornyl acetate (L-(-)-Bornyl acetate) is a less active enantiomer of (+)-Bornyl acetate. Isolated from hyssop oil, it possesses antifungal, highly active whitening, and antioxidant properties, and it has potential applications in cosmeceutical materials. It downregulates proinflammatory cytokines in vitro and in vivo, reduces the number of total cells, neutrophils, and macrophages in BALF, attenuates histologic lung alterations, decreases the wet-to-dry weight ratio in BALF, and inhibits the activation of NF-kappa-B inhibitor alpha, extracellular regulated protein kinases, c-JunN-terminal kinase, and p38 mitogen-activated protein kinase.
Chemical Properties
| Molecular Formula | C12H20O2 |
| Molecular Weight | 196.29 |
| CAS Numbers | 5655-61-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C[C@@]12[C@H](OC(C)=O)C[C@@](C1(C)C)(CC2)[H] |
Storage and Handling
0C Short Term, -20C Long Term
References
Chen N, et al. Inhibition of lung inflammatory responses by bornyl acetate is correlated with regulation of myeloperoxidase activity. J Surg Res. 2014 Jan;186[1] 436-4