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YZ129
AOB17666
CAS No: 1643120-60-8
Chemical Name: 4-(Isoquinolin-6-ylamino)naphthalene-1,2-dione
988 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Overview
Novel HSP90 inhibitor, targeting the calcineurin-NFAT signaling and HSP90 client network for glioblastoma (GBM) therapy
Chemical Properties
| Molecular Formula | C19H21N2O2 |
| Molecular Weight | 300.32 |
| CAS Numbers | 1643120-60-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4-(Isoquinolin-6-ylamino)naphthalene-1,2-dione |
| InChl Key | NYDMVPHEEBVAHT-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C19H12N2O2/c22-18-10-17(15-3-1-2-4-16(15)19(18)23)21-14-6-5-13-11-20-8-7-12(13)9-14/h1-11,21H |
| SMILES Code | O=C(C1=CC=CC=C1C(NC2=CC=C(C=NC=C3)C3=C2)=C4)C4=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
YZ129; YZ 129; YZ-129
References
Liu Z, et al. Discovery of Small-Molecule Inhibitors of the HSP90-Calcineurin-NFAT Pathway against Glioblastoma. Cell Chem Biol. 2018 Nov 30. pii: S2451-9456(18)30431-8.
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