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Pentachloropseudilin
AOB33969
CAS: 69640-38-6
Chemical Name: PClP; 2,4-Dichloro-6-(3,4,5-trichloro-1H-pyrrol-2-yl)phenol
AOBIOUS launched this product in 2019
CITATIONS - Publications That Use AOBIOUS Product
1) Blood Adv. 2024 May 1;8(17):4714–4726.
3) Blood Adv (2024) 8 (17): 4714–4726
789 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Overview
Selective Myosin-1 (Myo1) inhibitor, suppressing transforming growth factor-β (TGF-β) activity by accelerating cell-surface type II TGF-β receptor turnover in target cells
Chemical Properties
| Molecular Formula | C10H4Cl5NO |
| Molecular Weight | 331.40 |
| CAS Numbers | 69640-38-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2,4-Dichloro-6-(3,4,5-trichloro-1H-pyrrol-2-yl)phenol |
| InChl Key | FBRLLYYPGGXCKT-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C10H4Cl5NO/c11-3-1-4(9(17)5(12)2-3)8-6(13)7(14)10(15)16-8/h1-2,16-17H |
| SMILES Code | OC1=C(C2=C(Cl)C(Cl)=C(Cl)N2)C=C(Cl)C=C1Cl |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
Pentachloropseudilin; PClP
References
1) Chung CL, Wang SW, Martin R, Knölker HJ, Kao YC, Lin MH, Chen JJ, Huang YB, Wu DC, Chen CL. Pentachloropseudilin inhibits transforming growth factor-β (TGF-β) activity by accelerating cell-surface type II TGF-β receptor turnover in target cells. Chembiochem. 2018 Jan 25.
2) Gupta P, Martin R, Knölker HJ, Nihalani D, Kumar Sinha D. Myosin-1 inhibition by PClP affects membrane shape, cortical actin distribution and lipid droplet dynamics in early Zebrafish embryos. PLoS One. 2017 Jul 5;12(7)
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