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WX2-43
AOB13346
CAS: 723754-14-1
Chemical Name: 4-(((4-Chlorophenyl)amino)methyl)-N,N-diethylaniline
49 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $75.65 | Total: $378.25 |
| 1 | 10 | $64.08 | Total: $640.80 |
| 1 | 25 | $54.29 | Total: $1,357.25 |
| 1 | 50 | $46.28 | Total: $2,314.00 |
| 1 | 100 | $40.05 | Total: $4,005.00 |
Overview
Novel potent PRMT5 specific inhibitor, specifically blocking KLF4-mediated transcription and cell survival, suppressing breast tumor progression
Chemical Properties
| Molecular Formula | C17H21ClN2 |
| Molecular Weight | 288.82 |
| CAS Numbers | 723754-14-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4-(((4-Chlorophenyl)amino)methyl)-N,N-diethylaniline |
| InChl Key | OKEBKDNDKRWCCC-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H21ClN2/c1-3-20(4-2)17-11-5-14(6-12-17)13-19-16-9-7-15(18)8-10-16/h5-12,19H,3-4,13H2,1-2H3 |
| SMILES Code | CCN(CC)C1=CC=C(CNC2=CC=C(Cl)C=C2)C=C1 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
WX2-43; WX2 43; WX243
References
Z. Zhou et al.; A novel small-molecule antagonizes PRMT5-mediated KLF4 methylation for targeted therapy; Lancet
44:98-111 ( 2019).
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