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iST2-1
AOB36416
CAS: 1019158-02-1
Chemical Name: 2-(4-Methoxyphenyl)-1-((5-(2-nitrophenyl)furan-2-yl)methyl)pyrrolidine
249 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Overview
First-in-class ST2 inhibitor active in vivo
Chemical Properties
| Molecular Formula | C22H22N2O4 |
| Molecular Weight | 378.43 |
| CAS Numbers | 1019158-02-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2-(4-Methoxyphenyl)-1-((5-(2-nitrophenyl)furan-2-yl)methyl)pyrrolidine |
| InChl Key | RBVNERPDMZVXIP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C22H22N2O4/c1-27-17-10-8-16(9-11-17)20-7-4-14-23(20)15-18-12-13-22(28-18)19-5-2-3-6-21(19)24(25)26/h2-3,5-6,8-13,20H,4,7,14-15H2,1H3 |
| SMILES Code | O=[N+](C1=CC=CC=C1C2=CC=C(CN3C(C4=CC=C(OC)C=C4)CCC3)O2)[O-] |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
i-ST2-1; iST2 1; iST2-1
References
Ramadan AM, Daguindau E, Rech JC, Chinnaswamy K, Zhang J, Hura GL, Griesenauer B, Bolten Z, Robida A, Larsen M, Stuckey JA, Yang CY, Paczesny S. From proteomics to discovery of first-in-class ST2 inhibitors active in vivo. JCI Insight. 2018 Jul 25;3(14). pii: 99208. doi: 10.1172/jci.insight.99208. [Epub ahead of print] PubMed PMID: 30046004; PubMed Central PMCID: PMC6124397.