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10058-F4
AOB9898
CAS: 403811-55-2
Chemical Name: 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Overview
Novel c-Myc inhibitor, markedly increasing valproic acid-induced cell death in Jurkat and CCRF-CEM T-lymphoblastic leukemia cells
Chemical Properties
| Molecular Formula | C12H11NOS2 |
| Molecular Weight | 249.35 |
| CAS Numbers | 403811-55-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 5-[(4-ethylphenyl)methylene]-2-thioxo-4-thiazolidinone |
| InChl Key | FMTMQUAQVIOWNQ-UTANGQNASA-M |
| InChl Code | InChI=1S/C12H11NOS2/c1-2-8-3-5-9(6-4-8)7-10-11(14)13-12(15)16-10/h3-7H,2H2,1H3,(H,13,14,15)/b10-7+ |
| SMILES Code | O=C1NC(S/C1=C/C2=CC=C(CC)C=C2)=S |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
10058-F4; 10058F4; 10058 F4.
References
1) Zhang M, et al. Inhibition of c-Myc by 10058-F4 induces growth arrest and chemosensitivity in pancreatic ductal adenocarcinoma. Biomed Pharmacother. 2015 Jul;73:123-8. doi: 10.1016/j.biopha.2015.05.019. Epub 2015 Jun 1. PubMed PMID: 26211592.
2:) Mu Q, et al., 10058-F4, a c-Myc inhibitor, markedly increases valproic acid-induced cell death in Jurkat and CCRF-CEM T-lymphoblastic leukemia cells. Oncol Lett. 2014 Sep;8(3):1355-1359. Epub 2014 Jun 24. PubMed PMID: 25120723; PubMed Central PMCID: PMC4114592.