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Darolutamide (ODM-201)
AOB87622
CAS: 1297538-32-9
Chemical Name: ODM-201; BAY-1841788; N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide
999 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $9.35 | Total: $46.75 |
| 1 | 10 | $7.92 | Total: $79.20 |
| 1 | 25 | $6.71 | Total: $167.75 |
| 1 | 50 | $5.72 | Total: $286.00 |
| 1 | 100 | $4.95 | Total: $495.00 |
Overview
Novel full and high-affinity antagonist of the androgen receptor (AR)
Chemical Properties
| Molecular Formula | C19H19ClN6O2 |
| Molecular Weight | 389.85 |
| CAS Numbers | 1297538-32-9 |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide |
| InChl Key | ANGUXJDGJCHGOG-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C25H29N5O/c1-19-8-9-22-23(27-19)6-3-7-24(22)29-16-14-28(15-17-29)12-10-20-4-2-5-21(18-20)30-13-11-26-25(30)31/h2-9,18H,10-17H2,1H3,(H,26,31) |
| SMILES Code | O=C(C1=NNC(C(O)C)=C1)N[C@@H](C)CN2N=C(C3=CC=C(C#N)C(Cl)=C3)C=C2 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
ODM-201; ODM 201; ODM201; Darolutamide; Nubeqa.
References
1) Bastos DA, Antonarakis ES. Darolutamide For Castration-Resistant Prostate Cancer. Onco Targets Ther. 2019 Oct 23;12:8769-8777. doi: 10.2147/OTT.S197244. eCollection 2019. PubMed PMID: 31695432; PubMed Central PMCID: PMC6816030.2) Markham A, Duggan S. Darolutamide: First Approval. Drugs. 2019 Nov;79(16):1813-1818. doi: 10.1007/s40265-019-01212-y. Review. PubMed PMID: 31605368.
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