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CYD19
AOB11460
CAS: 2415281-52-4
Chemical Name: N-(2-Amino-4-fluorophenyl)-4-(((4-((5-methyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)thio)methyl)benzamide
AOBIOUS launched this product in 2021
CITATIONS - Publications That Use AOBIOUS Product
4932 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $26.35 | Total: $131.75 |
| 1 | 10 | $22.32 | Total: $223.20 |
| 1 | 25 | $18.91 | Total: $472.75 |
| 1 | 50 | $16.12 | Total: $806.00 |
| 1 | 100 | $13.95 | Total: $1,395.00 |
Overview
Novel potent CBP/p300-Snail interaction inhibitor, suppressing tumor growth and metastasis in wild-type p53-expressing cancer, forming a high-affinity interaction with the evolutionarily conserved arginine-174 pocket of Snail protein, reversing Snail-mediated epithelial-mesenchymal transition (EMT) and impairs EMT-associated tumor invasion and metastasis
Chemical Properties
| Molecular Formula | C24H21FN8OS |
| Molecular Weight | 488.55 |
| CAS Numbers | 2415281-52-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | N-(2-Amino-4-fluorophenyl)-4-(((4-((5-methyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)thio)methyl)benzamide |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
CYD 19, CYD-19; Snail/HDAC-IN-1
References
1) Hong-Mei Li et al., A potent CBP/p300-Snail interaction inhibitor suppresses tumor growth and metastasis in wild-type p53-expressing cancer, Science Advances 22 Apr 2020: Vol. 6, no. 17, eaaw8500
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