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MEISi-1
AOB11439
CAS: 446306-43-0
Chemical Name: 4-(2-(Benzylamino)-2-oxoethoxy)-N-(2,3-dimethylphenyl)benzamide
89 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $67.15 | Total: $335.75 |
| 1 | 10 | $56.88 | Total: $568.80 |
| 1 | 25 | $48.19 | Total: $1,204.75 |
| 1 | 50 | $41.08 | Total: $2,054.00 |
| 1 | 100 | $35.55 | Total: $3,555.00 |
Overview
Novel MEIS inhibitor (MEISi), significantly inhibiting MEIS-luciferase reporters in vitro and inducing murine (LSKCD34low cells) and human (CD34+, CD133+, and ALDHhi cells) HSC self-renewal ex vivo
Chemical Properties
| Molecular Formula | C24H24N2O3 |
| Molecular Weight | 388.47 |
| CAS Numbers | 446306-43-0 |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4-(2-(Benzylamino)-2-oxoethoxy)-N-(2,3-dimethylphenyl)benzamide |
| InChl Key | MNJQVNZAPZMEDA-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C24H24N2O3/c1-17-7-6-10-22(18(17)2)26-24(28)20-11-13-21(14-12-20)29-16-23(27)25-15-19-8-4-3-5-9-19/h3-14H,15-16H2,1-2H3,(H,25,27)(H,26,28) |
| SMILES Code | O=C(NC1=CC=CC(C)=C1C)C2=CC=C(OCC(NCC3=CC=CC=C3)=O)C=C2 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
MEISi-1; MEISi 1; MEISi1
References
1) Turan RD, Albayrak E, Uslu M, Siyah P, Alyazici LY, Kalkan BM, Aslan GS, Yucel D, Aksoz M, Tuysuz EC, Meric N, Durdagi S, Gulbas Z, Kocabas F. Development of Small Molecule MEIS Inhibitors that modulate HSC activity. Sci Rep. 2020 May 14;10(1):7994. doi: 10.1038/s41598-020-64888-3. PMID: 32409701; PMCID: PMC7224207.