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Endosidin2
AOB0156
CAS No: 350509-48-7
Chemical Name: ES2; 3-Fluorobenzoic acid [(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide
994 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $11.05 | Total: $55.25 |
| 1 | 10 | $9.36 | Total: $93.60 |
| 1 | 25 | $7.93 | Total: $198.25 |
| 1 | 50 | $6.76 | Total: $338.00 |
| 1 | 100 | $5.85 | Total: $585.00 |
Overview
Novel inhibitor of exocytosis and endosomal recycling in both plant and human cells, binding to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex, enhancing plant vacuolar trafficking
Chemical Properties
| Molecular Formula | C15H12FIN2O3 |
| Molecular Weight | 414.17 |
| CAS Numbers | 350509-48-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 3-Fluoro-benzoic acid, (2E)-2-[(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide |
| InChl Key | UIADDCURKKFTFW-QGMBQPNBSA-N |
| InChl Code | InChI=1S/C15H12FIN2O3/c1-22-13-6-9(5-12(17)14(13)20)8-18-19-15(21)10-3-2-4-11(16)7-10/h2-8,20H,1H3,(H,19,21)/b18-8+ |
| SMILES Code | FC1=CC(C(N/N=C/C2=CC(I)=C(O)C(OC)=C2)=O)=CC=C1 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
ES2; Endosidin2; Endosidin-2
References
1) Zhang, C., Brown, M.Q., van de Ven, W., et al. Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis. Proc. Natl. Acad. Sci. USA 113(1), E41-E50 (2016).
