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Ml081
AOB1543
CAS 316-42-7
Chemical Name: (2S,3R,11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine hydrochloride; Emetine dihydrochloride; NSC-33669; ML-081
1000 Items
Overview
Potent, RBBP9>RBBP9 reversible inhibitor
Chemical Properties
| Molecular Formula | C29H40N2O4·2HCl· |
| Molecular Weight | 553.56 |
| CAS Numbers | 316-42-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-2H-benzo[a]quinolizine dihydrochloride hydrate |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Lee et al. (2008), Ipecacuanha: the South American vomiting root; J R Coll. Physicians Edinb., 38 355
2) Sun et al. (2019), Emetine Exhibits Anticancer Activity in Breast Cancer Cells as an Antagonist of Wnt/β-catenin Signaling; Oncol. Rep., 42 1735