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SZL-P1-41
AOB2911
CAS No: 222716-34-9
Chemical Name: 3-(2-Benzothiazolyl)-6-ethyl-7-hydroxy-8-(1-piperidinylmethyl)-4H-1-benzopyran-4-one; SKP2 E3 Ligase Inhibitor III
AOBIOUS launched this product in 2016
CITATIONS - Publications That Use AOBIOUS Product
188 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Overview
Novel Skp2 inhibitor, selectively suppressing Skp2 SCF E3 ligase activity
Chemical Properties
| Molecular Formula | C24H24N2O3S |
| Molecular Weight | 420.52 |
| CAS Numbers | 222716-34-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 3-(2-benzothiazolyl)-6-ethyl-7-hydroxy-8-(1-piperidinylmethyl)-4H-1-benzopyran-4-one |
| InChl Key | JKIXLEKBXHMXTN-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C24H24N2O3S/c1-2-15-12-16-22(28)18(24-25-19-8-4-5-9-20(19)30-24)14-29-23(16)17(21(15)27)13-26-10-6-3-7-11-26/h4-5,8-9,12,14,27H,2-3,6-7,10-11,13H2,1H3 |
| SMILES Code | O=C1C(C2=NC3=C(C=CC=C3)S2)=COC4=C1C=C(CC)C(O)=C4CN5CCCCC5 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Chan, C.H., Morrow, J.K., Li, C.F., et al. Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression. Cell. 154(3), 556-568 (2013).
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