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MLS001158554
AOB11103
CAS N/A
Chemical Name: (S)-N-((S)-1-((4-Ethylphenyl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide hydrochloride
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $143.65 | Total: $718.25 |
| 1 | 10 | $121.68 | Total: $1,216.80 |
| 1 | 25 | $103.09 | Total: $2,577.25 |
| 1 | 50 | $87.88 | Total: $4,394.00 |
| 1 | 100 | $76.05 | Total: $7,605.00 |
Overview
MLS001158554 is a novel inhibitor of human cytomegalovirus (HCMV) identified through high-throughput screening. It was part of a study published in the Journal of Medicinal Chemistry, where five distinct inhibitors were characterized for their antiviral activity against HCMV .ACS Publications
Mechanism of Action:
The study demonstrated that each of the five compounds, including MLS001158554, inhibited a specific stage of HCMV replication. This suggests that MLS001158554 may target a particular step in the viral life cycle, though the exact mechanism remains to be fully elucidated .PMC
Chemical Properties
| Molecular Formula | C29H31ClN4O2 |
| Molecular Weight | 503.04 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (S)-N-((S)-1-((4-Ethylphenyl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide hydrochloride |
Storage and Handling
0C Short Term -20C Long Term
References
1) Arun Kapoor et al., Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus; J. Med. Chem. 2020, 63, 8, 3896–3907