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Arimoclomol Maleate
AOB15814
CAS 289893-26-1
Chemical Name: N-[(2R)-2-Hydroxy-3-piperidin-1-ylpropoxy]-1-oxidopyridin-1-ium-3-carboximidoyl chloride Maleate
999 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $9.35 | Total: $46.75 |
| 1 | 10 | $7.92 | Total: $79.20 |
| 1 | 25 | $6.71 | Total: $167.75 |
| 1 | 50 | $5.72 | Total: $286.00 |
| 1 | 100 | $4.95 | Total: $495.00 |
Overview
Novel stimulator of a normal cellular protein repair pathway, activating the heat shock response and acting at Hsp70, for treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease
Chemical Properties
| Molecular Formula | C18H24ClN3O7 |
| Molecular Weight | 429.85 |
| CAS Numbers | 289893-26-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | N-[(2R)-2-Hydroxy-3-piperidin-1-ylpropoxy]-1-oxidopyridin-1-ium-3-carboximidoyl chloride Maleate |
| SMILES Code | Cl/C(C1=C[N+]([O-])=CC=C1)=NOC[C@H](O)CN2CCCCC2.OC(/C=CC(O)=O)=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
BRX-220
References
1) Rakonczay Z Jr, et al. Nontoxic heat shock protein coinducer BRX-220 protects against acute pancreatitis in rats. Free Radic Biol Med. 2002 Jun 15;32(12):1283-92.
2) Phukan J. Arimoclomol, a coinducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis. IDrugs. 2010 Jul;13(7):482-96.