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YE6144
AOB16858
CAS: 3065657-02-2
Chemical Name: (S,E)-N1-(6-Fluoro-3-(2-(6-morpholinopyridazin-3-yl)vinyl)-1H-indazol-5-yl)butane-1,2-diamine hydrochloride
8 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $195.46 | Total: $977.30 |
| 1 | 10 | $165.57 | Total: $1,655.67 |
| 1 | 25 | $140.27 | Total: $3,506.80 |
| 1 | 50 | $119.58 | Total: $5,978.80 |
| 1 | 100 | $103.48 | Total: $10,347.93 |
Overview
Novel selective IRF5 inhibitor, inhibiting the phosphorylation of IRF5 in both human PBMCs and mouse splenocytes
Chemical Properties
| Molecular Formula | C21H27ClFN7O |
| Molecular Weight | 447.94 |
| CAS Numbers | 3065657-02-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (S,E)-N1-(6-Fluoro-3-(2-(6-morpholinopyridazin-3-yl)vinyl)-1H-indazol-5-yl)butane-1,2-diamine hydrochloride |
| SMILES Code | CC[C@@H](CNC1=CC2=C(NN=C2/C=C/C3=CC=C(N4CCOCC4)N=N3)C=C1F)N.[H]Cl |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Ban T, et al. Genetic and chemical inhibition of IRF5 suppresses pre-existing mouse lupus-like disease. Nat Commun. 2021 Jul 19;12(1):4379.