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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $28.90 | Total: $144.50 |
| 1 | 10 | $24.48 | Total: $244.80 |
| 1 | 25 | $20.74 | Total: $518.50 |
| 1 | 50 | $17.68 | Total: $884.00 |
| 1 | 100 | $15.30 | Total: $1,530.00 |
Overview
Adavivint (SM04690) is a selective inhibitor of the typical Wnt signaling pathway. In SW480 cells, EC50=19.5 nM was measured using high-throughput TCFLEF reporter gene experiments.
Chemical Properties
| Molecular Formula | C29H24FN7O |
| Molecular Weight | 505.55 |
| CAS Numbers | 1467093-03-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4cncc(-c5cccc(F)c5)c4[nH]3)c2c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Yazici Y , Mcalindon T E , Fleischmann R , et al. A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee results of a 24-week, randomized, controlled, phase 1 study[J]. Osteoarthritis & Cartilage, 2017, 25[10] 1598.