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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $114.75 | Total: $573.75 |
| 1 | 10 | $97.20 | Total: $972.00 |
| 1 | 25 | $82.35 | Total: $2,058.75 |
| 1 | 50 | $70.20 | Total: $3,510.00 |
| 1 | 100 | $60.75 | Total: $6,075.00 |
Overview
Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened (Smo) receptor agonist, with an EC50 of 1 nM and Ki values between 0.5 and 2.3 nM for Smo. Hh-Ag1.5-mediated reprogramming breaks the quiescent state of non-injured hepatic stem cells and thus rescues liver failure. Hh-Ag1.5 induced differentiation of hiPSCs into skin precursor cells, spinal motor neurons and spinal sensory neurons.
Chemical Properties
| Molecular Formula | C28H26ClF2N3OS |
| Molecular Weight | 526.04 |
| CAS Numbers | 612542-14-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN[C@H]1CC[C@@H](CC1)N(Cc1cccc(c1)-c1ccncc1)C(=O)c1sc2c(F)ccc(F)c2c1Cl |
Storage and Handling
0C Short Term, -20C Long Term
References
King RW. Roughing up Smoothened chemical modulators of hedgehog signaling. J Biol. 2002 Nov 6;1[2] 8.