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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $168.30 | Total: $841.50 |
| 1 | 10 | $142.56 | Total: $1,425.60 |
| 1 | 25 | $120.78 | Total: $3,019.50 |
| 1 | 50 | $102.96 | Total: $5,148.00 |
| 1 | 100 | $89.10 | Total: $8,910.00 |
Overview
CWP232228, a potent and selective Wnt ?-catenin signaling inhibitor, antagonizes the binding of ?-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting the growth of breast cancer and liver cancer stem cells (CSC) without toxicity.
Chemical Properties
| Molecular Formula | C33H36N7O7P |
| Molecular Weight | 673.66 |
| CAS Numbers | 1144044-02-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(N([C@](CN1CC2=CC=CC3=CN(C)N=C23)([H])N4[C@@H](CC5=CC=C(OP(O)(O)=O)C=C5)C1=O)N(CC=C)CC4=O)NCC6=CC=CC=C6 |
Storage and Handling
0C Short Term, -20C Long Term
References
Jang GB, et al. Wnt?-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells. Cancer Res. 2015 Apr 15;75[8] 1691-702.