Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $34.85 | Total: $174.25 |
| 1 | 10 | $29.52 | Total: $295.20 |
| 1 | 25 | $25.01 | Total: $625.25 |
| 1 | 50 | $21.32 | Total: $1,066.00 |
| 1 | 100 | $18.45 | Total: $1,845.00 |
Overview
CUR61414 is a cell-permeable inhibitor of Hedgehog signaling pathway (IC50
Chemical Properties
| Molecular Formula | C31H42N4O5 |
| Molecular Weight | 550.69 |
| CAS Numbers | 334998-36-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cccc(CN([C@H]2C[C@H](N(Cc3ccc4OCOc4c3)C2)C(=O)N2CCNCC2)C(=O)CC(C)(C)C)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Williams JA, et al. Identification of a small molecule inhibitor of the hedgehog signaling pathway effects on basal cell carcinoma-like lesions.Proc Natl Acad Sci U S A. 2003 Apr 15;100[8] 4616-21. Epub 2003 Apr 4.