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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $27.20 | Total: $136.00 |
| 1 | 10 | $23.04 | Total: $230.40 |
| 1 | 25 | $19.52 | Total: $488.00 |
| 1 | 50 | $16.64 | Total: $832.00 |
| 1 | 100 | $14.40 | Total: $1,440.00 |
Overview
FzM1.8 is an allosteric FZD4 agonist with a pEC50 of 6.4. FzM1.8 binds to FZD4, promotes TCFLEF transcriptional activity in the absence of any WNT ligand, and activates the WNT?-catenin pathway.
Chemical Properties
| Molecular Formula | C18H14N2O4 |
| Molecular Weight | 322.31 |
| CAS Numbers | 2204290-85-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC(=O)c1cc(O)cc(NC(=O)Nc2ccc3ccccc3c2)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Riccio G, et al. A Negative Allosteric Modulator of WNT Receptor Frizzled 4 Switches into an Allosteric Agonist. Biochemistry. 2018 Feb 6;57[5] 839-851.