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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $31.45 | Total: $157.25 |
| 1 | 10 | $26.64 | Total: $266.40 |
| 1 | 25 | $22.57 | Total: $564.25 |
| 1 | 50 | $19.24 | Total: $962.00 |
| 1 | 100 | $16.65 | Total: $1,665.00 |
Overview
K-756 is a direct and selective inhibitor of tankyrase (TNKS), inhibiting the ADP-ribosylation activity of TNKS1 [IC50 = 31 nM] and TNKS2 [IC50 = 36 nM].
Chemical Properties
| Molecular Formula | C24H27N5O3 |
| Molecular Weight | 433.5 |
| CAS Numbers | 130017-40-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc2ncnc(N3CCC(CN4Cc5ccccc5NC4=O)CC3)c2cc1OC |
Storage and Handling
0C Short Term, -20C Long Term
References
Okada-Iwasaki R, et al. The Discovery and Characterization of K-756, a Novel Wnt?-Catenin Pathway Inhibitor Targeting Tankyrase. Mol Cancer Ther. 2016 Jul;15[7] 1525-34.