2,5-dimethyl Celecoxib

2,5-dimethyl Celecoxib

AT35610

CAS 457639-26-8

More details

1000 Items

$59.80

$59.80 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $39.10 Total: $195.50
110 $33.12 Total: $331.20
125 $28.06 Total: $701.50
150 $23.92 Total: $1,196.00
1100 $20.70 Total: $2,070.00

Overview

2,5-dimethyl Celecoxib is a celecoxib derivative and a targeted inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), a key enzyme in the PGE2 synthesis pathway of inflammatory mediators.

Chemical Properties

Molecular FormulaC18H16F3N3O2S
Molecular Weight395.4
CAS Numbers457639-26-8
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC1=CC(C2=CC(=NN2C2=CC=C(C=C2)S(N)(=O)=O)C(F)(F)F)=C(C)C=C1

Storage and Handling

0C Short Term, -20C Long Term

References

Majchrzak-Celi?ska A, et al. COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt?-catenin pathway and COX-2PGE2EP4 signaling in glioblastoma cells. BMC Cancer. 2021 May 3;21[1] 493.