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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $163.20 | Total: $816.00 |
| 1 | 10 | $138.24 | Total: $1,382.40 |
| 1 | 25 | $117.12 | Total: $2,928.00 |
| 1 | 50 | $99.84 | Total: $4,992.00 |
| 1 | 100 | $86.40 | Total: $8,640.00 |
Overview
BI-4142 is an orally active, potent and selective HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.
Chemical Properties
| Molecular Formula | C28H27N9O2 |
| Molecular Weight | 521.57 |
| CAS Numbers | 2682003-36-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(C=C)N1CCN(C2=NC=C3N=CN=C(NC4=CC=C(OC=5C=CC6=C(N=CN6C)C5)C(=C4)C)C3=N2)CC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Wilding B, et al. Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling. Nat Cancer. 2022 Jul;3[7] 821-836.