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![[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate](https://img.aobious.com/img/p/4/7/5/0/5/47505-large_default.webp "[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate")
![[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate](https://img.aobious.com/img/p/4/7/5/0/5/47505.jpg "[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate")
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $103.70 | Total: $518.50 |
| 1 | 10 | $87.84 | Total: $878.40 |
| 1 | 25 | $74.42 | Total: $1,860.50 |
| 1 | 50 | $63.44 | Total: $3,172.00 |
| 1 | 100 | $54.90 | Total: $5,490.00 |
Overview
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) is a broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. Induces apoptosis and inhibits cancer cell growth in vitro.
Chemical Properties
| Molecular Formula | C81H113N19O14 |
| Molecular Weight | 1576.91 |
| CAS Numbers | 3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)C[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC3=CC=CC=C3)NC([C@@H](CC4=CNC5=C4C=CC=C5)NC([C@H](CCC(N)=O)NC([C@@H](CC6=CC=CC=C6)NC([C@H]7N(C([C@H](CCCCN)NC([C@H]8N(C([C@@H](CCCNC(N)=N)N)=O)CCC8)=O)=O)CCC7)=O)=O)=O)=O)=O)=O)=O.CC(O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Holst et al [2003] High constitutive signaling of the ghrelin receptor - identification of a potent inverse agonist. Mol.Endocrinol. 17 2201 PMID