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BMS-191011
AOB1942
CAS No: 202821-81-6
Chemical Name: BMS-A; 3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3H)-one
450 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $9.35 | Total: $46.75 |
| 1 | 10 | $7.92 | Total: $79.20 |
| 1 | 25 | $6.71 | Total: $167.75 |
| 1 | 50 | $5.72 | Total: $286.00 |
| 1 | 100 | $4.95 | Total: $495.00 |
Overview
Potent Maxi-K channel opener; Neuroprotectant
Chemical Properties
| Molecular Formula | C16H10ClF3N2O3 |
| Molecular Weight | 370.71 |
| CAS Numbers | 202821-81-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 3-[(5-chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3H)-one |
| InChl Key | QKOWACXSXTXRKA-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C16H10ClF3N2O3/c17-12-5-6-13(23)10(7-12)8-22-15(24)25-14(21-22)9-1-3-11(4-2-9)16(18,19)20/h1-7,23H,8H2 |
| SMILES Code | O=C1OC(C2=CC=C(C(F)(F)F)C=C2)=NN1CC3=C(O)C=CC(Cl)=C3 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
BMS-191011; BMS 191011; BMS191011; UNII-LW7MXS978N; Bms-a.
References
1) Romine, J.L., Martin, S.W., Meanwell, N.A., et al. 3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3H)-one, BMS-191011: Opener of large-conductance Ca2+-activated potassium (maxi-K) channels, identification, solubility, and SAR. J. Med. Chem. 50(3), 528-542 (2007).
2) Mori, A., Suzuki, S., Sakamoto, K., et al. BMS-191011, an opener of large-conductance Ca2+-activated potassium channels, dilates rat retinal arterioles in vivo. Biol. Pharm. Bull. 34(1), 150-152 (2011).
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