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TAK-438 (Vonoprazan Fumarate )
AOB87404
CAS: 1260141-27-2 or 881681-01-2
Chemical Name: Vonoprazan fumurate; 1-[5-(2-Fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine fumarate
10000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Overview
Novel potassium-competitive acid blocker (P-CAB)
Chemical Properties
| Molecular Formula | C21H20FN3O6S |
| Molecular Weight | 461.46 |
| CAS Numbers | 1260141-27-2 or or 881681-01-2 (fumarate) |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine fumarate |
| InChl Key | ROGSHYHKHPCCJW-WLHGVMLRSA-N |
| InChl Code | InChI=1S/C17H16FN3O2S.C4H4O4/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,23)14-5-4-8-20-11-14;5-3(6)1-2-4(7)8/h2-9,11-12,19H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+ |
| SMILES Code | CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=C/C(=O)O)C(=O)O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
TAK438, TAK-438, TAK 438, Vonoprazan Fumarate, Vonoprazan, Takecab
References
1) Arikawa Y, Nishida H, Kurasawa O, Hasuoka A, Hirase K, Inatomi N, Hori Y, Matsukawa J, Imanishi A, Kondo M, Tarui N, Hamada T, Takagi T, Takeuchi T, Kajino M. Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamin e fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB). J Med Chem. 2012 May 10;55(9):4446-56. doi: 10.1021/jm300318t. Epub 2012 Apr 30. PubMed PMID: 22512618.