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MB-3 (Butyrolactone 3)
AOB5007
CAS No:778649-18-6
Chemical Name: Butyrolactone 3; Gcn5 Inhibitor 1; (2S,3R)-4-Methylidene-5-oxo-2-propyloxolane-3-carboxylic acid
980 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $23.80 | Total: $119.00 |
| 1 | 10 | $20.16 | Total: $201.60 |
| 1 | 25 | $17.08 | Total: $427.00 |
| 1 | 50 | $14.56 | Total: $728.00 |
| 1 | 100 | $12.60 | Total: $1,260.00 |
Overview
Histone acetyltransferase GCN5 inhibitor
Chemical Properties
| Molecular Formula | C9H12O4 |
| Molecular Weight | 184.19 |
| CAS Numbers | 778649-18-6 |
| Solubility | DMSO |
| Stock Solution Guide | DMF: 13 mg/ml DMSO: 14 mg/ml Ethanol: 14 mg/ml PBS (pH 7.2): 2 mg/ml |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | rel-tetrahydro-4-methylene-5-oxo-2R-propyl-3S-furancarboxylic acid |
| InChl Key | SRQUTZJZABSZRQ-NKWVEPMBSA-N |
| InChl Code | InChI=1S/C9H12O4/c1-3-4-6-7(8(10)11)5(2)9(12)13-6/h6-7H,2-4H2,1H3,(H,10,11)/t6-,7+/m0/s1 |
| SMILES Code | O=C1C([C@@H](C(O)=O)[C@H](CCC)O1)=C |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
Butyrolactone 3
References
1) Biel, M., et al. Design, synthesis, and biological evaluation of a small-molecule inhibitor of the histone acetyltransferase Gcn5. Angewandte Chemie International Edition 43, 3974-3976 (2004).
2) Kuhn, A.N., et al. Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation. RNA 15, 153-175 (2009).
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