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PD144723
AOB0865
CAS No: 148553-50-8
Chemical Name: Lyrica; 3-Isobutyl GABA; CI-1008; (S)-3-(Aminomethyl)-5-methylhexanoic acid
90000 Items
Discontinued Product : Pregabalin (Cat. No. AOB0865) has been withdrawn from sale for commercial reasons.
Overview
GABA analog/ligand at α2δ subunit of voltage-dependent Ca2+ channels
Chemical Properties
| Molecular Formula | C8H17NO2 |
| Molecular Weight | 159.23 |
| CAS Numbers | 148553-50-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (S)-3-(Aminomethyl)-5-methylhexanoic acid |
| InChl Key | AYXYPKUFHZROOJ-ZETCQYMHSA-N |
| SMILES Code | CC(C)C[C@H](CN)CC(O)=O |
| PubChem ID | 5486971 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
Lyrica; 3-Isobutyl GABA; CI-1008; Pregabalin
References
1) Field et al (2001) Pregabalin may represent a novel class of anxiolytic agents with a broad spectrum of activity. Br.J.Pharmacol. 132 1 PMID: 11156553
2) Kumar et al (2010) Evidence that prega. reduces neuropathic pain by inhibiting the spinal release of glutamate. J.Neurochem. 113 552 PMID: 20132471
3) Arain (2009) Pregabalin in the management of partial epilepsy. Neuropsych.Dis.Treat. 5 407
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