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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
Grapiprant (AAT-007) is a selective EP4 receptor antagonist. Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor (IC50: 35 nM, Ki: 24 nM).
Chemical Properties
| Molecular Formula | C26H29N5O3S |
| Molecular Weight | 491.61 |
| CAS Numbers | 415903-37-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCc1nc2c(C)nc(C)cc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Vito VD, et al. Detection and quantification of the selective EP4 receptor antagonist CJ-023423 [grapiprant] in canine plasma by HPLC with spectrofluorimetric detection. J Pharm Biomed Anal. 2016 Jan 25;118 251-8.