Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $77.35 | Total: $386.75 |
| 1 | 10 | $65.52 | Total: $655.20 |
| 1 | 25 | $55.51 | Total: $1,387.75 |
| 1 | 50 | $47.32 | Total: $2,366.00 |
| 1 | 100 | $40.95 | Total: $4,095.00 |
Overview
EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and 16.2 nM, respectively, while displaying minimal activity (IC50s >10 ?M) against human EP1, EP2, and EP3 receptors.
Chemical Properties
| Molecular Formula | C23H21F3N4O3 |
| Molecular Weight | 458.43 |
| CAS Numbers | 2287259-07-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC=Cc1nnn(Cc2ccc(cc2)C(F)(F)F)c1C(=O)N[C@@H](C)c1ccc(cc1)C(O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Yang JJ,