Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $334.05 | Total: $1,670.25 |
| 1 | 10 | $282.96 | Total: $2,829.60 |
| 1 | 25 | $239.73 | Total: $5,993.25 |
| 1 | 50 | $204.36 | Total: $10,218.00 |
| 1 | 100 | $176.85 | Total: $17,685.01 |
Overview
TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.
Chemical Properties
| Molecular Formula | C24H22FNO4S |
| Molecular Weight | 439.5 |
| CAS Numbers | 2332972-26-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(N[C@@H](C)C1=CC=C(C(O)=O)C=C1)(=O)C=2C3=C(SC2CC4=CC=C(F)C=C4)COCC3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Lu W, et al. Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer. EMBO Mol Med. 2021 Jan 11;13[1] e12798.