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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $37.40 | Total: $187.00 |
| 1 | 10 | $31.68 | Total: $316.80 |
| 1 | 25 | $26.84 | Total: $671.00 |
| 1 | 50 | $22.88 | Total: $1,144.00 |
| 1 | 100 | $19.80 | Total: $1,980.00 |
Overview
Tebufelone is a potent in vitro inhibitor of CO , a novel non-steroidal anti-inflammatory drug (NSAID) belonging to the di-tert-butylphenol (DTBP) class that has shown potent anti-inflammatory, analgesic and anti-reticulitis properties in various animal models. Tebufelone potently inhibits the formation of prostaglandins (PGE2) and blocks the formation of lipoxygenase pathway products [leukotriene (LTB4)] in rat macrophages (IC50 = 20 microM) and human whole blood (IC50 = 22 microM) in vitro. = 20 microM) and human whole blood (IC50 = 22 microM) from the formation of lipoxygenase pathway products [leukotriene (LTB4)] in vitro.
Chemical Properties
| Molecular Formula | C20H28O2 |
| Molecular Weight | 300.44 |
| CAS Numbers | 112018-00-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC1=C(C(C)(C)C)C=C(C(CCCC#C)=O)C=C1C(C)(C)C |
Storage and Handling
0C Short Term, -20C Long Term
References
Powell JH, et al. Antipyretic activity of tebufelone [NE-11740] in man. Agents Actions Suppl. 1991 ; 32 45-49.