Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
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Overview
NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].
Chemical Properties
| Molecular Formula | C11H24N2O2 |
| Molecular Weight | 216.32 |
| CAS Numbers | 51857-17-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(NCCCCCCN)(OC(C)(C)C)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Aug 21.