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Overview
Aspirin (Acetylsalicylic Acid) is a COX inhibitor that inhibits COX1 and COX2 (IC50=5210 ?gmL) with selective, irreversible, and oral activity. Aspirin is also a histone deacetylase inhibitor that up-regulates the cell cycle blocking protein, p21. Aspirin has a variety of activities. Aspirin has anti-inflammatory, antipyretic and analgesic, and antiplatelet aggregation activities.
Chemical Properties
| Molecular Formula | C9H8O4 |
| Molecular Weight | 180.16 |
| CAS Numbers | 50-78-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | |
| InChl Key | |
| InChl Code | |
| SMILES Code | CC(=O)OC1=CC=CC=C1C(O)=O |
Storage and Handling
0C Short Term, -20C Long Term
Synonyms
References
Kopp E, et al. Science, 1994, 265[5174], 956-959.